Systemic arthritis attacks the synovial membrane that covers the cartilage of the joints and secretes a lubricating fluid: the synovium.
This fluid also allows the joints to move without pain.
That said, systemic arthritis can affect the hands, feet, shoulders, knees, elbows or wrists. As well, they can occur when the patient's immune system goes into overdrive. As a result, it causes a cascade of reactions that lead to the exaggerated production of a substance called cytosine. This substance causes inflammation of the joints, resulting in pain and stiffness, and then deformity of the joint.
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Les arthrites systémiques peuvent être une maladie généralisée
On the Verywell Health website, Doctor Grant Hughes tells us how arthritis can affect the whole body: "Fever, fatigue, weakness, anemia, nodules, dry eyes, dry mouth, pulmonary fibrosis, pleural effusion (excessive fluid in the lungs), nervous problems, gastrointestinal complications, skin complications and kidney disease are examples of extra-articular disease.... This is just a sample of a more complete list of possible systemic effects that can occur with arthritis and related rheumatic diseases. In fact, extra-articular manifestations can develop even when there is little active joint involvement. »
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What is systemic rheumatoid arthritis?
In addition to swollen joints, the systemic form of juvenile rheumatoid arthritis is characterized by a fever and a pale pink rash. It can also affect internal organs such as the heart, liver, spleen and lymph nodes. The systemic form, sometimes called Still's disease, affects 20% of children with JRA. A small percentage of children develop arthritis in many joints and may have severe arthritis that continues into adulthood.
This definition is offered to us by the WebMD website, which we have freely translated for you to educate you on the issue of systemic arthritis.